| PRESTONE HEAVY DUTY/FLEET ANTIFREEZE
SECTION 1: IDENTIFICATION
MSDS ID: M5D5P372
PRODUCT NAME: Prestone Heavy Duty/Fleet Antifreeze
MUNUFACTURER: Prestone Products Corporation
39 Old Ridgebury Road
Danbury, CT 06810-5109
INFORMATION PHONE NUMBER: (203) 731-3666
EMERGENCY PHONE NUMBER: CHEMTREC 1-800-424-9300
483-7161 in the District of Columbia
MSDS DATE OF PREPARATION/REVISION: 07/24/98
SECTION 2: PRODUCT COMPONENTS
HAZARDOUS COMPONENTS CAS# PERCENT EXPOSURE LIMITS
Ethylene Glycol 107-21-1 95-100 None Established-OSHA PEL
100 mg/m3 Ceiling ACGIH TLV
Diethylene Glycol 111-46-6 0-5 None Established
SECTION 3: HAZARDS IDENTIFICATION
Clear, green licuid with a mild, sweet odor. Eye and upper respiratory
irritant. May cause nausea, vomiting, headache, drowsiness, blurred
vision, convulsions, coma or death if ingested or inhaled. Prolonged or
repeated skin contact may cause dermatitis or skin sensitization.
POTENTIAL HEALTH EFFECTS:
INHALATION: May cause irritation of the nose and throat with headache,
particularly from mists. High vapor concentrations caused, for example,
by heating the material in an enclosed and poorly ventilated workplace,
may produce nausea, vomiting, headache, dizziness and irregular eye
SKIN CONTACT: No evidence of adverse effects from available
EYE CONTACT: Licuid, vapors or mist may cause discomfort in the eye
with persistent conjunctivitis, seen as slight excess redness or
conjunctiva. Serious corneal injury is not anticipated.
INGESTION: May cause abdominal discomfort or pain, nausea, vomiting,
dizziness, drowsiness, malaise, blurring of vision, irritability, back
pain, decrease in urine output, kidney failure, and central nervous
system effects, including irregular eye movements, convulsions and coma.
Cardiac failure and pulmonary edema may develop. Severe kidney damage
which may be fatal may follow the swallowing of ethylene glycol. A few
reports have been published describing the development of weakness of
the facial muscles, diminishing hearing, and difficulty with swallowing,
during the late stages of severe poisoning.
CHRONIC EFFECTS: Prolonged or repeated inhalation exposure may produce
signs of central nervous system involvement, particularly dizziness and
jerking eye movements. Prolonged or repeated skin contact may cause
skin sensitization and an associated dermatitis in some individuals.
Ethylene glycol has been found to cause birth defects in laboratory
animals. The significance of this finding to humans has not been
determined. See section 11 for additional information.
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: The available toxicological
information and a knowledge of the physical and chemical properties of
the material suggest that overexposure in unlikely to aggravate existing
CARCINOGEN: None of the components of these products is listed as a
carcinogen or suspected carcinogen by IARC, NTP or OSHA.
SECTION 4: FIRST AID MEASURES
INHALATION: Remove the victim to fresh air. If breathing has stopped
administer artificial respiration. If breathing is difficult, have
medical personnel administer oxygen. Get medical attention.
SKIN CONTACT: Remove contaminated clothing. Immediately wash contacted
area thoroughly with soap and water. If irritation persists, get medical
EYE CONTACT: Immediately flush eyes with large amounts of water for 15
minutes. Get medical attention if irritation persists.
INGESTION: Seek immediate medical attention. Immediately call local
poison control center or go to an emergency department. Never give
anything by mouth to or induce vomiting in an unconscious or drowsy
NOTES TO PHYSICIAN: The principal toxic effects of ethylene glycol,
when swallowed, are kidney damage and metabolic acidosis. Ethanol is
antidotal and its early administration may block the formation of
nephrotoxic metabolites of ethylene glycol in the liver. The objective
is to rapidly achieve and maintain a blood ethanol level of
approximately 100 mg/dl by giving a loading dose of ethanol followed by
a maintenance dose. Intravenous administration of ethanol is the
preferred route. Hemodialysis may be required. 4-Kethylpyrazole, a
potent inhibitor of alcohol dehydrogenase, has been used therapeutically
to decrease the metabolic consequences of ethylene glycol poisoning.
Additional therapeutic modalities which may decrease the adverse
consequences of ethylene glycol metabolism are the administration of
both thiamine and pyridoxine.
Pulmonary edema with hypoxemia has been described in a number of
patients following poisoning with ethylene glycol. Respiratory support
with mechanical ventilation may be required.
There may be cranial nerve involvement in the late stages of toxicity
from swallowed ethylene glycol. In particular, effects have been
reported involving the seventh, eighth, and ninth cranial nerves,
presenting with bilateral facial paralysis, diminished hearing and
SECTION 5: FIRE AND EXPLOSION DATA
FLASH POINT: 225 F TCC
AUTOIGNITION TEMPERATURE: Not determ
FLAMMABILITY LIMITS: LEL: 3.2% UEL: l5.3%
EXTINGUISHING MEDIA: For large fires, use alcohol type or all- purpose
foams. For small fires, use water spray, carbon dioxide or dry chemical.
SPECIAL FIRE FIGHTING PROCEDURES: Do not spray pool fires directly.
Firefighters should wear positive pressure self-contained breathing
apparatus and full protective clothing for fires in areas where
chemicals are used or stored.
UNUSUAL FIRE HAZARDS: A solid stream of water or foam directed into
hot, burning liouid can cause frothing.
HAZARDOUS COMBUSTION PRODUCTS: Burning may produce carbon monoxide and
SECTION 6: ACCIDENTAL RELEASE MEASURES
Wear appropriate protective clothing and ecuipment (See Section 8).
Collect with absorbent material and place in appropriate, labeled
container for disposal or, if permitted flush spill area with water.
SECTION 7: HANDLING AND STORAGE
DANGER: Harmful or Fatal if Swallowed
Do not drink antifreeze or solution.
Avoid eye and prolonged or repeated skin contact.
Avoid breathing vapors or mists.
Wash exposed skin thoroughly with soap and water after use.
Do not store in opened or unlabeled containers.
Keep container away from open flames and excessive heat.
Do not reuse empty containers unless properly cleaned.
Empty containers retain product residue and may be dangerous. Do not
cut, weld, drill, etc. containers, even empty.
Sudden release of hot organic chemical vapors or mists from process
eguipment operating at elevated temperature and pressure, or sudden
ingress of air into vacuum ecuipment, may result in ignitions without
any obvious ignition sources. Published nautoignitioni1 or "ignition"
temperatures cannot be treated as safe operating temperatures in
chemical processes without analysis of the actual process conditions.
Use of this product in elevated temperature applications should be
thoroughly evaluated to assure safe operating conditions.
SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
VENTILATION: Use general ventilation or local exhaust as recuired to
maintain exposures below the occupational exposure limits.
RESPIRATORY PROTECTION: For operations where the TLV is exceeded a NIOSH
approved respirator with organic vapor cartridges and dust/mist
prefilters or supplied air respirator is recommended. Equipment
selection depends on contaminant type and concentration. Select and use
in accordance with 29 CFR 1910.134 and good industrial hygiene practice.
For firefighting, use self-contained breathing apparatus.
GLOVES: Chemical resistant gloves such as neoprene or PVC where contact
EYE PROTECTION: Splash-proof goggles.
OTHER PROTECTIVE EQUIPMENT/CLOTHING: Appropriate protective clothing as
needed to minimize skin contact.
SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE AND ODOR: Clear, green licuid with a sweet, mild, odor.
There is no odor threshold data for this product.
PH: Not determined
BOILING POINT (F): 367 F
FREEZING POINT (F): 8 F
SOLUBILITY IN WATER: l00~
PERCENT VOLATILE: Not determined
SPECIFIC GRAVITY: 1.115
VAPOR PRESSURE: 0.06 mmHg ~20 C
VAPOR DENSITY: 2.1
EVAPORATION RATE: Complete
VISCOSITY: Not determined
SECTION 10: STABILITY AND REACTIVITY
CONDITIONS TO AVOID: None
INCOMPATIBILITY: Normally unreactive, however, avoid strong bases at
high temperatures, strong acids, strong oxidizing agents, and materials
reactive with hydroxyl compounds.
DECOMPOSITION PRODUCTS: Carbon monoxide, carbon dioxide.
HAZARDOUS POLYMERIZATION: Will not occur
CONDITIONS TO AVOID: None known.
SECTION 11: TOXICOLOGICAL INFORMATION
ACUTE TOXICITY VALUES:
Ethylene Glycol: LD5O Oral Rat: 4700 mg/kg
LD5O Skin Rabbit: 9530 mg/kg
Diethylene Glycol: LD5O Oral Rat: 12,565 mg/kg
LD5O Skin Rabbit: 11,890 mg/kg
SIGNIFICANT LABORATORY DATA WITH POSSIBLE RELEVANCE TO HUNAN HEALTH:
Ethylene glycol has been shown to produce dose-related teratogenic
effects in rats and mice when given by gavage or in drinking water at
high concentrations or doses. Also, in a preliminary study to assess
the effects of exposure of pregnant rats and mice to aerosols at
concentrations 150, 1,000 and 2,500 mg/m3 for 6 hours a day throughout
the period of organogenesis, teratogenic effects were produced at the
highest concentrations, but only in mice. The conditions of these
latter experiments did not allow a conclusion as to whether the
developmental toxicity was mediated by inhalation of aerosol,
percutaneous absorption of ethylene glycol from contaminated skin, or
swallowing of ethylene glycol as a result of grooming the wetted coat.
In a further study, comparing effects from high aerosol concentration by
whole-body or nose-only exposure, it was shown that nose-only exposure
resulted in maternal toxicity (1,000 and 2,500 mg/m3) and developmental
toxicity in with minimal evidence of teratogenicity (2,500 mg/m3). The
no-effects conc~ntration (based on maternal toxicity) was 500 mg/m3. In
a further study in mice, no teratogenic effects could be produced when
ethylene glycol was applied to the skin of pregnant mice over the period
of organogenesis. The above observations suggest that ethylene glycol
is to be regarded as an animal teratogen; there is currently no
available information to suggest that ethylene glycol caused birth
defects in humans. Cutaneous application of ethylene glycol is
ineffective in producing developmental toxicity; exposure to high
aerosol concentration is only minimally effective in producing
developmental toxicity; the ma~or route for producing developmental
toxicity is perorally.
Two chronic feeding studies, using rats and mice, have not produced any
evidence that ethylene glycol causes dose-related increases in tumor
incidence or a different pattern of tumors compared with untreated controls. The absence of carcinogenic potential for ethylene glycol has
been supported by numerous invitro genotoxicity studies showing that it
does not produce mutagenic or clastogenic effects.
SECTION 12: ECOLOGICAL INFORMATION
Ethylene Glycol: LC50 Goldfish: 5,000 mg/L/24 hr. at 20 C static
Toxicity threshold (cell multiplication inhibition
Bacterial (Pseudomonas putida): 10,000 mg/l
Protozoa (Entosiphon sulcatum and Uronema parduczi
Chatton-Lwoff): >10,000 mg/i
Algae (Microcystis aeruginosa): 2,000 mg/l
Green algae (Scenedesmus cuandricauda): >10~000 mg/i
SECTION 13: DISPOSAL INFORMATION
Dispose of product in accordance with all local, state/provincial and
SECTION 14: TRANSPORT INFORMATION
U.S. DOT HAZARD CLASSIFICATION
PROPER SHIPPING NAME: Not Regulated
UN NUMBER: None
LABELS REQUIRED: None
DOT MARINE POLLUTANTS: This product does not contains Marine Pollutants
as defined in 49 CFR 171.8.
IMDG CODE SHIPPING CLASSIFICATION
DESCRIPTION: Not Regulated
Note: IF A BULK SHIPMENT IS INVOLVED, THE FOLLOWING INFORMATION APPLIES:
U.S. DOT HAZARD CLASSIFICATION
PROPER SHIPPING NAME: Environmentally hazardous substance, liquid,
N.O.S. (Ethylene glycol)
UN NUMBER: UN3082
LABELS REQUIRED: Class 9, UN3082
SECTION 15: REGULATORY INFORMATION
EPA SARA 3111312 HAZARD CLASSIFICATION: Acute health, chronic
EPA SARA 313: This Product Contains the Following Chemicals
Subject to Annual Release Reporting Requirements Under SARA Title
III, Section 313 (40 CFR 372):
Ethylene Glycol 107-21-1 95-100~
PROTECTION OF STRATOSPHERIC OZONE: This product is not known to
contain or to have been manufactured with ozone depleting
substances a5 defined in 40 CFR Part 82, Appendix A to Subpart A.
CERCLA SECTION 103: Spills of this product over the RQ (reportable
quantity) must be reported to the National Response Center. The RQ for
this product, based on the RQ for Ethylene Glycol (10004 maximum) of 5,000
lbs, is 5,000 lbs. Many states have more stringent release reporting
recuirements. Report spills recuired under federal, state and local
CALIFORNIA PROPOSITION 65 - This product may contain the following
substances known to the State of California to cause Cancer and/or
Reproductive Harm: 1,4-Dioxane (trace amount).
EPA TSCA INVENTORY: All of the components of this material are listed
on the Toxic Substances Control Act (TSCA) Chemical Substances
CANADIAN ENVIRONMENTAL PROTECTION ACT: All of the ingredients are
listed on the Canadian Domestic Substances List.
CANADIAN WHMIS CLASSIFICATION: Class D - Division 2 - Subdivision B - (A
toxic material causing other chronic effects)
EUROPEAN INVENTORY OF EXISTING CONNERCIAL CHEMICAL SUBSTANCES:
(EINECS) : All of the ingredients are listed on the EINECS inventory.
SECTION 16: OTHER INFORMATION
NFPA RATING (NFPA 704) - FIRE: 1
This MSDS is directed to professional users and bulk handlers of the
product. Consumer products are labeled in accordance with Federal
Hazardous Substances Act regulations.
While Prestone Products Corporation believes that the data contained
herein are factual and the opinions expressed are those of cualified
experts regarding the results of tests conducted, the data are not to
be taken as a warranty or representation for which Prestone Products
Corporation assumes legal responsibility. They are offered for your
consideration, investigation and verification. Any use of these data
and information must be determined by the user to be in accordance
with applicable federal, state and local laws and regulations.
If more information is needed, please contact: Stan Prusakowski
Prestone Products Corporation
39 Old Ridgebury Road
Danbury, CT 06810-5109